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Hermann Bujard, a molecular biologist who was behind the Tet-Off system worked for many years at the ZMBH in Heidelberg. He sadly passed away on the 31st of July at the age of 86. I thought I would post a message to the ISTT Blog, reflecting how important some of his ideas and technical achievements have been for the development of transgenic technologies.
The Board of Directors of the International Society for Transgenic Technology (ISTT) has the following comment on the ruling of the European Court of Justice (ECJ), which requires any that genome-edited organism shall be treated as GMO within the meaning of the European GMO Directive.
The ISTT, a scientific society representing the largest group of experts in the field of genome modification in animals, is surprised and disappointed that the court decided to focus on the method and not the product of genome editing and thus did not follow the recommendation of the court's Advocate General.
In a collaborative effort of USA, South Korean and Chinese laboratories, the authors describe the correction of a mutation in the MYBPC3 gene associated with hypertrophic cardiomyopathy, through gene-editing, using CRISPR tools. (Nature article detailing results).
