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TT2025

Standard Nomenclature

The International Society for Transgenic Technologies (ISTT) and the associated scientific journal Transgenic Research, would like to encourage all colleagues to adhere and follow adequately the standard nomenclature rules when describing mouse models.

The Mouse Genome Informatics Database is the authoritative source of official names for mouse genes, alleles, and strains. Nomenclature follows the rules and guidelines established by the International Committee on Standardized Genetic Nomenclature for Mice

Joint Position Article:

Montoliu Lluís & Whitelaw C. Bruce A. (2010) Using standard nomenclature to adequately name transgenes, knockout gene alleles and any mutation associated to a genetically modified mouse strain. Transgenic Research (ePub, 16 July 2010)

Extracted from the paper above:

"The International Society for Transgenic Technologies (ISTT) and the scientific journal, Transgenic Research, to which the ISTT is associated, have decided to promote the use of standard nomenclature for naming mouse strains, genes, mutations and alleles. In this regard, and according to ISTT aims and activities, ISTT will disseminate in its web site, blog, newsletter and Transgenic Technology (TT) meetings, information and recommendations to use standard nomenclature. Likewise, the correct use of rules and guidelines for standard nomenclature for naming mouse strains, genes, mutations and alleles will be enforced in subsequent articles submitted to Transgenic Research for publication, as it is already done in several other journals."

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Examples of use of standard nomenclature [see Montoliu & Whitelaw (2010) for a full descrption]

Nomenclature WEB Resources

Mouse Nomenclature Home Page at MGI-JAX

Tutorial at JAX on mouse nomenclature rules

Guidelines for Nomenclature of Genes, Genetic Markers, Alleles, and Mutations in Mouse and Rat

Guidelines for Nomenclature of Mouse and Rat Strains

International Committee on Standardized Genetic Nomenclature for Mice

Mouse Strain 129 Substrain Nomenclature

Nomenclature in KO alleles generated by KOMP-CSD and EUCOMM

International Laboratory Code Registry at ILAR

Scientific Journals enforcing Standard Nomenclature