ISTT Prize

The ISTT has established the ISTT Prize that publicly recognizes an individual for his/her outstanding contributions to the field of Transgenic Technologies and  is awarded at each Transgenic Technology (TT) Meeting. The ISTT Prize has been supported by genOway from its inception through TT2020 ISTT Prize winners receive an honorarium, an Honorary Membership in the ISTT and a sculpture of a mouse blastocyst created by the late Hungarian artist Mr. Bela Rozsnyay (1949-2019).

The ISTT Prize Committee is composed of the ISTT President, the ISTT Vice-President, the ISTT Past President and all previous ISTT Prize awardees.

13th ISTT Prize Awardee

Dr. Alexandra Joyner


The International Society for Transgenic Technologies (ISTT, Inc.) is delighted to announce that the 13th ISTT Prize will be awarded to Dr. Alexandra Joyner for her pioneering work on homologous recombination in embryonic stem cells. The ISTT Prize is awarded to investigators who have made outstanding contributions to the field of transgenic technologies. The selection of Dr. Joyner as the 13th ISTT Prize winner was made by the ISTT Prize Committee. This committee is composed of previous ISTT prize awardees; the ISTT President, Wojtek Auerbach, and Vice-president, Benoit Kanzler; and the CEO of genOway, Alexandre Fraichard. GenOway fully sponsors this prestigious award. The committee unanimously agreed that Dr. Joyner’s work has been essential in the field of transgenesis for the generation of unique mutant mouse lines to study mouse development, and for creating mouse models of human genetic diseases.

Born in Ontario, Canada, Dr. Joyner completed her undergraduate study at the University of Toronto and her Ph.D. at the Ontario Cancer Institute. As a postdoctoral Fellow in Gail Martin’s lab, she developed methods for introducing DNA into ES cells and cloned the mouse equivalents of important fly developmental genes. She set up her own lab in 1986 in Toronto at Mount Sinai Hospital’s newly created Samuel Lunenfeld Research Institute where she continued to work with mouse ES cells to create novel mutant mouse lines to enable gene trap, knock-in and fate mapping approaches, along with studying the roles of engrailed genes and sonic hedgehog signaling in development.

In 1994, she was invited to create a program in Developmental Genetics at New York University’s newly created Skirball Institute of Biomolecular Medicine, where she worked for the next 12 years before accepting her present position at Memorial Sloan Kettering Institute. She has continued to apply the techniques she developed for studies of development, regeneration and cancer, with a focus on the cerebellum.

Dr. Joyner has published approximately 200 scientific papers, has been an invited speaker (often giving the keynote address) at nearly 50 meetings, and has numerous awards and honors including: Medical Research Council of Canada Scientist (1992-1994); Howard Hughes Medical Institute Investigator (1997-2006); Elected Fellow, American Academy of Arts and Science (2007-present); President, Society for Developmental Biology (2009-2012); Elected Member, National Academy of Medicine (2009-present).

We are pleased that Dr. Joyner has agreed to receive the ISTT Prize to be given at TT2020 meeting, thus joining the list of previously honored scientists, including Lluis Montoliu (2019), Mario Capecchi (2017), Janet Rossant (2014), Allan Bradley (2013), Ralph Brinster (2011), Francis Stewart (2010), Brigid Hogan (2008), Charles Babinet (2007), Andras Nagy (2005), Qi Zhou (2004), Kenneth McCreath (2002) and Teruhiko Wakayama (2001). All ISTT Prize winners are given an honorary ISTT membership and a unique silver sculpture representing a mouse blastocyst created by the late Hungarian artist Béla Rozsnyay. Dr. Joyner will receive her prize during the virtual 16th Transgenic Technology Meeting (TT2020) that is hosted by the Weizmann Institute of Science in Rehovot, Israel on 26-28 October 2020.

Dr. Alexandra Joyner’s lab web page