TT2026

ISTT Affiliated Meetings

UPCOMING MEETINGS AND WORKSHOPS

 


The 2nd Midwest CRISPR Animal Modeling Symposium (M-CAMS) will again be hosted by the Purdue Institute for Cancer Research-Transgenic and Genome Editing Facility (TGEF) and held in West Lafayette, Indiana on March 13, 2026

REGISTER HERE 

We had so much fun last time, we are doing it all again: a morning of talks by some of our most beloved ISTT members-Guru, Zach Freeman, Tristan Kempston, Masato Ohtsuka and special guest Mark Budde, founder of Plasmidsaurus, a lunchtime workshop on designing animal models and an afternoon dedicated to tech talk. The afternoon Protocol Parade and Technical Roundtable will again cover all our standard protocols (superovulation, microinjection, electroporation, embryo transfer, cryopreservation, IVF rederivation) and will also feature 2 focus sessions this year: One on zygote electroporation/AAV/GONAD and another on Sequencing/Bioinformatics for Genotyping. We will talk about what we do the same, what we do differently and why. What's not working, what's working really well and why. What's tried and true, what's new and what's been around but we've been afraid to try. Tricks we are delighted to spread tips we are happy to share and secrets we are willing to divulge. And then we will keep the conversation going and the good times rolling at our CRISPR Mixer!

March 12, 2026

Pre-Symposium Workshop : Ensembl – Genome Browser

Jorge Batista da Rocha (trainer)  -  Full day workshop

March 13, 2026

Morning Talks – Session 1 : Animal Model Design with CRISPR/cas9

Tristan Kempston  -  Introduction to Gene Editing with CRISPR-Cas9
Chanabasavaiah Gurumurthy  -  RE-CREATING Existing Mouse Models into Novel Animal Models
Masato Ohtsuka  -  Integrase/Recombinase-Mediated Targeted Transgenesis: PITT and SCRIPT
Stephane Pelletier  -  eSPLIT and iSWAP: Streamlined Strategies and Design Principles for Conditional Allele Engineering using Short Artificial Introns

Morning Talks – Session 2 : Sequencing for Genotyping and Validation

Mark Budde  -  Co-Founder/CEO of Plasmidsaurus, Special Guest – How Sequencing Enables a Step Change in Scientific Discovery
Zachary Freeman  -  Bridging Past and Future: Validating Classic and Next-Generation Engineered Models Using Long-Read Sequencing

Lunch and Learn : Animal Model Design Workshop

Tristan Kempston  -  Designing CRISPR-based Mutations in Rodent Models

Protocol Parade and Technical Roundtable : All Hands on Tech

Focus session 1  -  Sequencing/Bioinformatics for Genotyping and Validation
(Experts on Tap: Zach Freeman, Fabien Delerue, Plasmidsaurus, Hedyeh Rahimian)
Focus session 2  -  Zygote Electroporation/AAV/iGONAD
(Experts on Tap: Fabien Delerue, Nobuko Yamanaka, Yasuhiro Moriizumi (BEX), Michael Sperber (NepaGene), VectorBuilder, Masato Ohtsuko)
Other topics  -  Genome Browsers; Pipette pullers; anesthetic machines; ICSI; Needles; Rabbits; Rats; Gene Editing Software and more
Other Experts on Tap  -  Jorge Batista da Rocha (Ensembl); Adair Oesterle (Microtul); Kim Matheny (Kent Scientific); Jesse Toumeh (VectorBuilder) and YOU

Chat with Mark Budde  -  Mark has graciously agreed to have an inspirational, sit down chat with grad students and any other interested parties


The 39th International Mammalian Genome Conference to be held at the beautiful Harpa Convention Center in Reykjavik, Iceland April 7-10, 2026

Registration for the 39th IMGC is now open. Early registration, abstract submission and scholarship application deadlines are January 7, 2026.

Invited speakers:
  • Fernando Pardo Manuel de Villena will present the Verne Chapman Lecture
  • David Beier will present the Bill Dove Lecture
  • Caroline Manet will present the Mary Lyon Lecture
  • Dwi Kemaladewi is the recipient of the IMGS President’s Award.

PAST MEETINGS AND WORKSHOPS

The 5th Oceania Transgenic and Assisted Reproductive Technologies (OTART) Symposium was held on 29–30 October 2025 at The University of Melbourne, Parkville, Australia. Click here for additional details


ISTT MEMBERS HAVE ACCESS TO RECORDED VIDEOS AND SELECTED SLIDES FROM EDUCATIONAL INITIATIVES SERIES WORKSHOPS

ISTT Educational Initiatives series - online workshops

Long-Read Sequencing in Practice: Practical Strategies for Design, Multiplexing, and Analysis

CRISPR gene editing has been effectively employed to streamline the production of genetically modified animal models for biomedical research. However, a notable limitation is the potential for on-target mutations that may have detrimental consequences. These bystander mutations often go undetected with conventional genotyping methods, such as PCR, and standard sequencing techniques. Accurately identifying targeted animals is crucial for evaluating the efficiency of creating genetically engineered (GE) animal models. Long-read sequencing (LRS) has revolutionized this process by enabling comprehensive characterization without the need for PCR amplification. This advancement eliminates the need for multiple sets of junction PCRs, simplifying the verification of insertion accuracy and aiding in the screening for random integrations.

Presenter: Dr. Monica Sentmanat, R&D Lead and a Senior Scientist at the Genome Engineering and Stem Cell Center at the McDonnell Genome Center in Washington University in St. Louis

23 February 2026

24 February 2026


ISTT Educational Initiatives series: Exploring the New Ensembl Genome Browser - two part workshop

This two part tutorial is an introduction to the new Ensembl genome browser (beta.ensembl.org), which presents genomic features for over 3,000 species
with a new user interface. Participants had the opportunity to learn about the range of data currently available through the new platform, gain hands-on experience in navigating the new Ensembl website to retrieve and
interpret data and learn about how this data might be informative for their research.

Workshop I, July 14th, 2025

Workshop II, July 16th, 2025


ISTT Educational Initiatives series:  Validation of Engineered Alleles

October 29, 2024

Presenters: Marie-Christine Birling, Guillaume Pavlovic and Lydia Teboul

Highlights:

  • Principles of genotyping and genomic validation
  • Validating random integrations
  • Validating targeted alleles
  • Validating edited alleles

ISTT Educational Initiatives series:  Standardized Genetic Nomenclature: A Critical Tool for Research Reproducibility and Visibility. A rose by any other name would not be a rose.

July 23th and 24th, 2024

  • Fernando Benavides, MD Anderson Cancer Center, Houston, Texas
  • Lauryl MJ Nutter, The Centre for Phenogenomics, The Hospital for Sick Children in Toronto, Canada.

ISTT Educational Initiatives series:  Global Shipping of Rodents & Cryopreserved Materials: A European & US Perspective

May 28th 2024

  • Auke Boersma, University of Veterinary Medicine, Vienna, Austria, European Mouse Mutant Archive (EMMA) –INFRAFRONTIER
  • Abby Chott, MMRRC and RRRC

ISTT Educational Initiatives series: Mating, Timing, Superovulation and Implantation  
  • Optimized workflow for efficient generation of large knock-in mouse models using a combination of IVF and CRISPR-mediated genome editing in C57BL/6 mice.
  • Improving superovulation efficiency and implantation rates

March 25th and 26th, 2024

  • Mitra Cowan, McGill University, Montreal, Quebec, Canada
  • Judy Hallett, Purdue University, West Lafayette, IN, USA 

ISTT Educational Initiatives series:  Non-surgical Embryo Transfer and Use of Cervical Manipulation for Induction of Pseudopregnancy in Recipient Mice 

Estrous cycle synchronization, Cytological profiling and estrous cycle determination, Cervical manipulation to induce pseudopregnancy, Non-surgical embryo transfer.

July 18th and July 20th, 2023.

  • Barbara Stone, Director of Animal Research and Director of Assisted Reproduction Sciences at ParaTechs Corporation, USA
  • Philip Damiani, Vice President of Laboratory and Scientific Operations at Embryotech Laboratories, USA

 International Course "Latest Advances in Genome Editing and ART Technologies in Laboratory Mice”
at the Laboratory Animal Biotechnology Unit of Institut Pasteur de Montevideo (Uruguay) in collaboration with ICGEB and Institut Pasteur in France.

May 15th to 19th, 2023

Program and Report


ISTT Educational Initiatives series:  Gene Editing via Mouse Embryo Electroporation Workshop 

May 24 and 25, 2023

  • Fabien Delerue, Macquarie University, Sydney, Australia
  • Fatima El Marjou, Institut Curie, Paris, France

Workshop on CRISPR genome editing in mice with an emphasis on GONAD and microinjection

at The Van Andel Research Institute in Grand Rapids, Michigan, USA , December 13-15, 2023.

Webpage 
Report
Manual for ISTT members can be found here

1st Spermatogenesis Conference, 8- 11 October 2023 in Dubrovnik, Croatia.

 


ISTT Educational Initiatives series:  Embryo Transfer in mice, oviductal and uterine, surgical and non-surgical

March 23, 2022; 4-6 pm Central European Time (9-10 am US Central time)

March 30, 2022; 8-10 am Central European Time

Instructors:

  • Thomas Kolbe, Assoc. Prof. Dr., Biomodels Austria, University of Veterinary Medicine Vienna
  • Rahmen Bin Ali, Animal Modeling Facility (AMF) NKI, Amsterdam, the Netherlands .

The 35th International Mammalian Genome Conference at the Westin Bayshore Hotel in Vancouver, BC, Canada July 17-20, 2022.


ISTT Educational Initiatives series: Designing Mouse Models

Nov 24, 2021 Session 1: Basics and general principles of designing mouse models including simple knockouts to large knock-ins and conditional alleles.

Dec 8, 2021 Session 2: Discussion of actual examples of mouse model designs including the loci/projects of the workshop participants.

Instructor: CB Gurumurthy, Director of Mouse Genome Engineering Core Facility, University of Nebraska Medical Center, Omaha, NE, USA.


11th Workshop on Innovative Mouse Models (IMM2021 - virtual)
Four Thursday Zoom sessions: June 3, 10, 17 and 24, 2021. There is no charge, but registration is required.
Hosts: Ivo Huijbers, Peter Hohenstein, Jos Jonkers, Paul Krimpenfort, Hein te Riele, Els Robanus-Maandag, Marian van Roon

Program   |    Report

28-29 APRIL 2020  CRISPR Gene Editing Course (Second Module)
BIOCEV campus, Prumyslova 595, Vestec, Czech Republic
Host: Czech Centre for Phenogenomics       Program   |    Report

27 APRIL 2020  Ensemble Browser Workshop (First Module)
BIOCEV campus, Prumyslova 595, Vestec, Czech Republic
Host: Czech Centre for Phenogenomics         Program   |    Report

22-26 April 2020     TAGC (The Allied Genetics Conference)
Gaylord National Resort & Convention Center, Washington  DC USA
Host: Genetics Society of America       Program   |   Report

23-26 October 2019     European Developmental Biology Congress
Provincial Auditorium of Alicante, Alicante Spain
Host: Juan Galceran Saez         Program   |   Report

14-17 October 2019     International Workshop on Genome Editing in Mammals Using CRISPR Tools
Institut Pasteur de Montevideo, Montevideo Uruguay   
Hosts: Martina Crispo, Ana Paula Mulet, Alejo Menchaca, Geraldine Schlapp, Ma Noel Meikle
Information     |     Report

19-21 June 2019     10th Workshop on Innovative Mouse Models (IMM2019)
Hosts: Ivo Huijbers, Peter Hohenstein, Jos Jonkers, Paul Krimpenfort, Hein te Riele, Els Robanus-Maandag, Marian van Roon, Anna Gandaglia
Program   |   Report

10-13 June 2019     14th FELASA Congress 2019
Host: FELASA     Program     |     Report

15-21 August 2018   NCBS Animal Care and Resource Center - Second Mouse Cryobiology/IVF Workshop
Host:  Aurelie Jory     Program   |   Report

3-6 June 2018    2ND Large Animal Genetic Engineering (LAGE) Summit, Park City UT, USA.
Host: Irina Polejaeva, Jon Oatley, Bruce Whitelaw   Program   |   Report

5-8 May 2018     CALAS-ASCAL 57th Symposium, Quebec,City, Quebec Canada
ISTT Representative:  Marina Gertsenstein     Report

16-20 April 2018      3rd Programmable Nucleases Course - Transgenesis Course, Prague, Czech Republic.
Host:  Radislav Sedlacek, Petr Kasparek     Report  |   Participants

23-24 November 2017     3rd Oceania Mouse Transgenic and Assisted Reproductive Technologies Symposium, Sydney Australia.
Host: Fabien Delerue, Irma Villaflor   Program | Report | Pictures

14-18 November 2017     CARD-Texas Mouse Reproductive Technologies Workshop, College Station TX, USA.
Host: Andrei Golovko, William Shawlot, Jan Parker-Thornburg, Toru Takeo   Report | Pictures | Course Picture

13-17 August 2017     11th Transgenic Animal Research Conference (TARC XI), Tahoe City CA, USA.
Host: Jim Murray     Report | Pictures

15-16 June 2017     9th Workshop on Innovative Mouse Models (IMM 2017), Leiden, The Netherlands.
Host: Jos Jonkers, Paul Krimpenfort, Werner Mueller, Hein te Riele, Els Robanus-Maandag, Marian van Roon, Sjef Verbeek   Report  |  Pictures

12-20 June 2017     TT-RIIP 2017: Transgenic Technologies in Modeling Human Diseases, Athens, Greece.
Host: Sylva Haralambous, Martina Crispo, Francina Langa Vives     Program | Report | Pictures

11-12 May 2017     Advances in Transgenic Animal Models and Techniques, Nantes, France.
Host: Sevérine Menoret    Report

24-28 October, 2016     CARD-IP Sperm and Embryo Cryopreservation Training Course, Paris, France
Host: Jean Jaubert     Report | Program and Pictures

13-16 June 2016     2016 FELASA Congress, Brussels, Belgium
Host: Boris Jerchow     Report  |  Pictures

11-14 June, 2016     55th Annual CALAS/ACSAL Symposium, Toronto, Canada
Host: Marina Gertsenstein     Report  |  Program

7-18 September 2015    International Course and Mini-Symposium: Advances in the Generation of Genetically Modified (GM) Animal Models, Montevideo, Uruguay.
Host: Martina Crispo, Alejo Menchaca

9-13 August 2015     10th Transgenic Animal Research Conference (TARC-X), Tahoe City, CA USA.
Host: Jim Murray

2-3 July 2015     Transgenic Animals and Genetic Engineering Techniques, Nantes, France.
Host: Sevérine Menoret, Ignacio Anegon

11-12 June 2015     8th Workshop on Innovative Mouse Models (IMM2015), Leiden, The Netherlands.
Host: Marian van Roon, Sjef Veerbeek. Program

15-19 Sept 2014     CARD-RPCI Mouse Sperm and Embryo Cryopreservation Course, Buffalo NY, USA.
Host: Naomi Nakagata, Aimee Stablewski, Jan Parker-Thornburg.

7-11 Oct 2013     CARD-CNB Mouse Sperm and Embryo Cryopreservation Course, Madrid Spain.
Host: Naomi Nakagata, Lluis Montoliu

11-15 Aug 2013     IX Transgenic Animal Research Conference, Tahoe City CA, USA.
Host: Jim Murray

13-14 June 2013     7th Workshop on Innovative Mouse Models (IMM2013), Leiden, The Netherlands.
Host: Marian van Roon, Sjef Verbeek

10 June 2013     Mouse sperm cryopreservation: Satellite workshop, Barcelona Spain.
Host: Jorge Sztein and Jesús Martínez.

7 June 2013     Technical advances in the generation of transgenic animals and in their applications, Nantes FR.
Host: Sevérine Menoret, Ignacio Anegon

8-10 May 2013     Managing Mouse Colonies: Genetics, Breeding & Welfare, Hinxton, Cambridge UK.
Host: James Bussell. Nikki Osborne

6-8 June 2012     Managing Mouse Colonies: Genetics, Breeding & Welfare, Hinxton, Cambridge UK.
Host: James Bussell

7-8 May 2012     EMMA Cryopreservation Workshop, Madrid Spain.
Host: Lluís Montoliu, Martin Fray

24-27 Jan 2012     Optimization of Murine Models in Research and III Practical Course CECs: Mouse sperm freezing, Valdivia Chile.
Host: Juan Manuel Baamonde, Jorge Sztein, Fernando Benavides

5-14 Dec 2011     Genetics of Laboratory Rodents, Montevideo UR.
Host: Martina Crispo

7-11- Aug 2011     VII Transgenic Animal Research Conference, Tahoe City CA, USA.
Host: Jim Murray

6 June 2011     Transgenesis and genome analysis, Nantes FR.
Host: Sevérine Menoret, Ignacio Anegon.

12-13 May 2011     6th Workshop on Innovative Mouse Models (IMM2011), Leiden, The Netherlands.
Host: Marian van Roon.

22-26 Nov 2010     Cryopreservation of Mouse Germplasm and Symposium on Animal Models and Cryopreservation, Campinas Brazil.
Host: Delma P. Alves, Marcus F. Corat, Jorge Sztein and Martina Crispo

13 Nov 2010     Focus on new transgenic models and their phenotyping, Montreal, Quebec CA.
Host: Jacinthe Sirois

4-5 Nov 2010     AISAL Symposium on Imaging and Translational Medicine, Imola IT.
Host: Marcello Raspa

14-17 June 2010     New paradigms in laboratory animal science, Helsinki Finland.
Host: FELASA/Belen Pintado

7 Nov 2009     Transgenesis: new developments and applications, Montreal QC, CA.
Host: Melanie Chagnon

17-21 Aug 2009     VII Transgenic Animal Research Conference, Tahoe City CA, USA.
Host: Jim Murray

25-26 June 2009     5th Workshop on Innovative Mouse Models (IMM2009), Leiden, The Netherlands.
Host: Marian van Roon

8 June 2009     Transgenesis: recent technical developments and applications, Nantes FR.
Host: Ignacio Anegon and Severine Menoret

24 Nov. – 5 Dec 2008     Genetics of Laboratory Rodents, Montevideo UR.
Host: Martina Crispo

10-12 March 2008     1st Meeting Brazilian Society Transgenic Technologies, Sao Paulo Brazil.
Host: Joao Bosco Pesquero

11-13 January 2008     Advances in Transgenic Animal Research, Houston TX USA.
Host: Jan Parker-Thornburg

7-8 June 2007     Transgenics – “Back to basics… and beyond”, London UK.
Host: Sarah Johnson