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Sunday, October 23, 2011  
10:00 - 12:00 ISTT Council Meeting  
15:00 - 18:00 Registration and Poster Set Up  
18:00 - 22.00 Pre Meeting Dinner Cruise upon the Starlite Princess Authentic Paddlewheeler  

Monday, October 24, 2011
08:45 - 09:00 Welcome Address: ISTT President, Organizing Committee  
Session 1. Mouse Genetics
Chair: Carlisle Landel, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA  
09:00 - 09:30 Genetic Background and Superovulation
Carlisle Landel
Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA
 
09:30 - 10:00 Coat Colour in Generation of Chimeras
Marina Gertsenstein
Toronto Centre of Phenogenomics, Toronto, ON, Canada
 
10:00 - 10:30 How to Name a Mouse - Mouse Strain, Gene and Allele Nomenclature
Howard Dene
The Jackson Laboratory, Bar Harbor, Maine, USA
 
10:30 - 11:00 Coffee Break  
Session 2. Mouse Models of Disease
Chair: Jan Parker-Thornburg, M. D. Anderson Cancer Center, Houston, TX, USA  
11:00 - 11:30 As Quiet as a Mouse: Use of Genetically Modified Mice to Study Hearing and Deafness
Andy K. Groves
Baylor College of Medicine, Houston, TX, USA
 
11:30 - 12:00 Development and Preclinical Evaluation of Therapies for Spinal Muscular Atrophy in Mice
Arthur Burghes
The Ohio State University, Columbus, OH, USA
 
12:00 - 13:30 Lunch and Posters  
Session 3: Animal Ethics, Welfare and Updated Regulations on Animal Experimentation
Chair: Johannes Wilbertz, Karolinska Institute, Stockholm, Sweden
13:30 - 14:00 Animal Ethics
Karin Blumer
Novartis International AG, Basel, Switzerland
 
14:00-14:30 New European Directive on the Protection of Animals used for Scientific Purposes: Impact on the Generation and Management of Genetically Modified Models
Belen Pintado
National Center of Biotechnology (CNB), CSIC, Madrid, Spain
 
14:30 - 15:00 Shifitng Research Animal Regulations and Accreditation Standards: Hobbling or Facilitating Sound Science?
Chris Newcomer
AAALAC, Frederick, MD, USA
 
15:00 - 15:30 Coffee Break  
15:30 - 17:30 Round Table: How to Run a Transgenic Unit
Chair: Tom Fielder, University of California-Irvine, CA, USA
Aimee B. Stablewski, Roswell Park Cancer Institute, Buffalo, NY, USA
Cheryl Bock, Duke Medical Center, Durham, NC, USA
Rebbeca Haffner, Weizmann Institute of Science, Rehovot, Israel
 
Session 4: ISTT Prize  
17:30 - 17:40 Presentation of the ISTT Prize Winner (by ISTT President)
Lluís Montoliu
National Center of Biotechnology (CNB), CSIC, Madrid, Spain
 
17:40 - 18:45 8th ISTT Prize for Outstanding Contributions to Transgenic Technologies
Mammalian Germline Modification
Ralph L. Brinster
University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA, USA
 
19:00 Wine, Beer, Cheese and Posters  


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Tuesday, October 25, 2011
Session 5. Fundamental Methods for Transgenic Core Facilities
Chair: Elizabeth Williams, TASQ, University of Queensland, Brisbane, QLD, Australia
09:00 - 09:30 Essentials of Microinjection
Charles Hawkins
Johns Hopkins University, Baltimore, MD, USA
 
09:30 - 10:00 Factors Affecting In Vitro Fertilization
Jan Parker-Thornburg
M. D. Anderson Cancer Center, Houston, TX, USA
 
10:00 - 10:30 International Germplasm Transfer
Kent Lloyd
University of California-Davis, CA, USA
 
10:30 - 11:00 Coffee Break  
Session 6: International Initiatives, Web Resources for Transgenic/KO Mice
Chair: Peter Sobieszczuk, Auckland, New Zealand
11:00 - 11:30 Finding your Transgenic Mouse/ES Cell Line/Gene with On-line Resources
Peter Sobieszczuk
Auckland, New Zealand
 
11:30 - 12:00 Germline Performance of Gene-Targeted ES Cell Clones Imported from the International Knockout Mouse Consortium by a Transgenic Core Facility
Thom Saunders
University of Michigan, Ann Arbor, MI, USA
 
12:00 - 12:30 The IKMC Web Portal: A single access point to mouse knockouts from the International Knockout Mouse Consortium
William Skarnes
Wellcome Trust Sanger Institute, Hinxton, UK
 
12:30 - 14:00 Posters & Light Lunch, Posters, EVEN numbers  
Session 7: New Technologies
Chair: Boris Jerchow, Max-Delbrück-Center for Molecular Medicine, Berlin-Buch, Germany
14:00 - 14:30 Authentic Rat Embryonic Stem Cells and Germline Transmission of Targeted Mutations
Qi-Long Ying
Center for Stem Cell and Regenerative Medicine, University of Southern California, LA, CA, USA
 
14:30 - 15:00 Pronuclear Injection-Based Mouse Targeted Transgenesis by Site-Specific Recombination
Masato Ohtsuka
Tokai University, School of Medicine, Isehara, Kanagawa, Japan
 
15:00 - 15:30 Development of Vibratory Microinjection Systems
Fujio Miyawaki
Tokyo Denki University, Saitama, Japan
 
15.30 - 16.00 The JAX Colony Management System (JCMS): An Extensible Colony and Phenotype Data Management System for Transgenic Mouse Colonies
Chuck Donnelly
The Jackson Laboratory, Bar Harbor, Maine, USA
 
16:00 - 16:15 Selected Short Oral Presentation
Recombinase Mediated Promoter Switching Enables two Different Transgene Expression Levels to be Achieved in a Single Line of Targeted Transgenic Mice
Ben Davies
Wellcome Trust Centre for Human Genetics, University of Oxford, UK
 
16:15 - 16:30 Selected Short Oral Presentation
A "Lymphoreporter" Mouse for in Vivo Imaging of Lymphangiogenesis in Development, Inflammation and Tumour Metastasis
Sagrario Ortega
Spanish National Cancer Research Center (CNIO), Madrid, Spain
 
16:30 - 17:30 Posters, ODD numbers  
17:30 - 19:30 ISTT General Assembly  
20:00 Conference Banquet  


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Wednesday, October 26, 2011
Session 8: Beyond Mouse Transgenesis
Chair: Lluís Montoliu, National Center of Biotechnology (CNB), CSIC, Madrid, Spain
09:00 - 09:30 An Introduction to Non-Mouse Models                        
Bruce Whitelaw
The Roslin Institute, University of Edinburgh, Midlothian, Scotland, UK
 
09:30 - 10:00 Transgenic Pigs as Models for Translational Biomedical Research
Eckhard Wolf
University of Munich, Munich, Germany
 
10:00 - 10:30 The use of Transgenic Zebrafish to Investigate Biological Processes in Vivo
Robert Kelsh
Centre for Regenerative Medicine, University of Bath, Bath, UK
 
10:30 - 11:00 Coffee Break  
Session 9: Animal Biotechnology
Chair: Wojtek Auerbach, Regeneron Pharmaceticals, Inc., Tarrytown, NY, USA
11:00 - 11:30 The Regulation and Politics of Food from Genetically Engineered Animals
Alison L. Van Eenennaam
University of California-Davis, CA, USA
 
11:30 - 12:00 Suppression of Bird Flu Transmission in Transgenic Chickens
Helen Sang

The Roslin Institute, University of Edinburgh, Midlothian, Scotland, UK
 
12:00 - 12:30 Beyond the Mouse - Novel Genetically Engineered Animals
Edward Weinstein
Sigma Advanced Genetic Engineering Labs, St. Louis, MO, USA
 
12:30 - 12:45 Selected Short Oral Presentation
Production of Transgenic Sheep by Inhibin α shRNA
Xiangyang Miao
Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China
 
12.45 - 13.00 Selected Short Oral Presentation
Targeted Transgene Integration in Mouse Embryos using "Open Source" Zinc Finger Nucleases
Mario Hermann
Institute of Laboratory Animal Sciences, University of Zürich, Zürich, Switzerland
 
13:00 - 14:30 Lunch and Posters  
Session 10: Manipulating the Rat Genome
Chair: Thom Saunders, University of Michigan, Ann Arbor, MI, USA
14:30 - 15:00 Mutating the Rat Genome with Transposons
Joseph Ruiz
Transposagen Inc., Lexington, KY, USA
 
15:00 - 15:30 The Power of Rat Models - Targeted Nucleases
Aron Geurts
Medical College of Wisconsin, Milwaukee, WI, USA
 
  Final Session: Award Ceremony and Concluding Remarks
Chair: Thom Saunders, University of Michigan, Ann Arbor, MI, USA
 
15:30 - 15.40
Introduction to the ISTT Young Investigator Award
Thom Saunders, Vice-President of the ISTT
Paul Sheiffele & Lisa Aronov, inGenious Targeting Laboratory
 
15:40 - 15:55 Short talk by the 1st ISTT Young Investigator Award - TT2011
Generate Animal Models by Stem Cells Technology
Xiao-Yang Zhao
State Key Lab of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, PR China
 
15:55 - 16:15 Diplomas for the ISTT Registration Awards 
TT2011 Best Poster Awards
Presentation of TT2013 Meeting
Concluding Remarks
 
16:15
End of TT2011 Meeting

 


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